Death. edit. Burial of de Soto. De Soto died of a fever on 21 May 1542, in the native village of Guachoya. Historical sources disagree as to whether de Soto ...See more

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Spanish conquistador Hernando de Soto dies, ending a three-year journey for gold that took him halfway across what is now the United States.See more

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5 Sept 2025 — Hernando de Soto (born c. 1496/97, Jerez de los Caballeros, Badajoz, Spain—died May 21, 1542, along the Mississippi River [in present-day ...See more

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Spanish explorer Hernando DeSoto died of a fever while searching for gold in Florida and the territory north of the Gulf of Mexico.

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2 Aug 2023 — He died on May 21, 1542, in Ferriday, Louisiana. Members of his crew sank his body in the river that he had discovered. By that time, almost ...See more

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3 Oct 2018 — The governor died on May 21, 1542, of fever. In order to perpetuate the deception of having the Indians believe he was a god, expedition members ...See more

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by H de Soto — It was not long after the return crossing the de Soto was struck with a fever and fell deathly ill. He never recovered. Hernando de Soto died May 21, 1542.See more

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May 21, 1542, Hernando de Soto died of a fever at the age of 46. Hernando de Soto's men were anxious to conceal his death from the American Indians.See more

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21 May 2025 — Spanish explorer Hernando de Soto died of fever at “Guachoya,” believed to be modern-day Lake Village in Chicot County.See more

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Burial of De Soto – De Soto died in his camp on the shores of the Mississippi, June 5th, 1542, and was entombed at midnight in its flood, which still sings ...See more

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